Description: Human secreted Programmed Cell Death 1 Ligand 1 (PD-L1)- Fc fusion protein, also known as CD274 and B7 homolog 1 (B7- H1), GenBank Accession No. NM_014143, amino acids 19-239, expressed in a HEK293 cell expression system. MW = 52 kDa.
Synonyms: PDL1, B7H1,PDCD1LG1, PDCD1L1, PDCD1 Ligand 1
Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Formulated in: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Stability: >6 months at –70°C. Avoid freeze/thaw cycles.
References: 1. Freeman, G.J., et al., J Exp Med. 2000 Oct 2;192(7):1027-34. 2. Dong, H., et al., Nat Med. 1999 Dec;5(12):1365-9.
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