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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
biopioneerinc/LDN193189, 2.03mg/1/SM-005
产品编号:SM-005
市  场 价:¥2600.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$130.00
品      牌: biopioneerinc
公      司:biopioneerinc
公司分类:
biopioneerinc/LDN193189, 2.03mg/1/SM-005
商品介绍

LDN193189 is a highly potent cell permeable small molecule BMP inhibitor; inhibiting BMP type I receptors ALK2 (IC50: 5 nM), ALK3 (IC50: 30 nM) and ALK6 (TGFβ1/BMP signaling) and subsequent SMAD1, SMAD5, and SMAD8 phosphorylation (1, 2). It only has weak effect on ALK4, ALK5 and ALK7. LDN-193189 shows significant in vivo clinical utility, inhibiting FOP and ectopic ossification and a potential agent in the treatment of NSCLC lung tumors. Using LDN193189 can accelerates developmental timing and converts human pluripotent stem cells into nociceptors (3).

品牌介绍

BioPioneer Inc专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。

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