Description: Neutralizing recombinant human antibody (clone 1B8, IgG1 subclass) recognizing the PD-L1 binding region of human PD-1, expressed in a 293 freestyle cell expression system. MW = 50 kDa and 25 kDa for the heavy and light chain portions, respectively.
Application: Useful as a control inhibitor of PD-1 binding using the PD-1:PD-L1[Biotinylated] Inhibitor Screening Assay Kit, BPS Bioscience, Catalog #72003.
Formulated in: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Stability: >6 months at –80°C
References: 1. Shinohara, T., et al., Genomics. 1994 Oct;23(3):704-6. 2. James, E.S., et al., Genes Immun. 2005 Aug;6(5):430-7.
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