Description:Mature form of disulfide-bonded homodimer which is biologically activeSource:CHO cellMW:Predicted MW: monomer = 13 kDa, dimer = 26 kDaSDS-PAGE:monomer = 16 kDa (reducing condition), dimer = 32 kDa (non-reducing condition)(Due to glycosylation, rhBMP-2 migrates as a 16 kDa protein under reducing conditions and as a 32 kDa protein under non-reducing conditions in SDS-PAGE).Bioactivity:Fully active (determined by its ability to induce alkaline phosphatase production in ATDC5 chondrogenic cells); Typical ED50 = 50-100 ng/mLPurity: > 98% by SDS-PAGE and RP-HPLC analysisEndotoxin: < 0.1="" eu/?g="" rhbmp-2="" as="" determined="" by="" the="" lal="" methodpreservative:nonesterility:0.2="" membrane-filtered="" and="" packaged="" aseptically.qc="" tests:sds-page,="" maldi-tof="" and="" rp-hplcformulation:lyophilized="" from="" a="" sterile="" filtered="" solution="" of="" 10="" mm="" sodium="" citrate,="" ph="" 3.5reconstitution:add="" sterile="" distilled="" water="" to="" a="" concentration="" of="" no="" less="" than="" 0.1="" mg/ml.="" further="" dilutions="" should="" be="" made="" in="" appropriate="" buffers.storage="" and="" stability:upon="" receiving,="" store="" the="" product="" at="">